Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003842.5

p.C129S

c.385T>A

Surrounding Variants

2 papers

NM_003842.5

p.C129S

c.386G>C

1 paper

NM_003842.5

p.P128fs

c.382_383fs

1 paper

NM_003842.5

p.T131fs

c.391_392fs

1 paper

NM_003842.5

p.T132I

c.395C>T

1 paper

NM_003842.5

p.R133G

c.397A>G

1 paper

NM_003842.5

p.V136L

c.406G>T

1 paper

NM_003842.5

p.V136L

c.406G>C

1 paper

NM_003842.5

p.E141G

c.422A>G

1 paper

NM_003842.5

p.F144L

c.432C>G

1 paper

NM_003842.5

p.R145L

c.434G>T

1 paper

NM_003842.5

p.D148A

c.443A>C

1 paper

NM_003842.5

p.E146_D148delFs

c.436_442del7