Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003842.5

p.Y103C

c.308A>G

Surrounding Variants

1 paper

NM_003842.5

p.G100fs

c.298_299fs

1 paper

NM_003842.5

p.H106H

c.318C>T

1 paper

NM_003842.5

p.N108fs

c.322_323fs

1 paper

NM_003842.5

p.K98N

c.294A>T

1 paper

NM_003842.5

p.K98N

c.294A>C

1 paper

NM_003842.5

p.C97del1

c.289_290delGCA

1 paper

NM_003842.5

p.N108delFs

c.324delA

1 paper

NM_003842.5

p.D109A

c.326A>C

1 paper

NM_003842.5

p.F112L

c.336C>G

1 paper

NM_003842.5

p.G122Splc

c.365-374C>T

1 paper

NM_003842.5

p.P128fs

c.382_383fs

1 paper

NM_003842.5

p.C129S

c.385T>A