Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003842.5

p.M1T

c.2T>C

Surrounding Variants

1 paper

NM_003842.5

p.R4R

c.12G>C

1 paper

NM_003842.5

p.G5*

c.13G>T

1 paper

NM_003842.5

p.G5E

c.14G>A

1 paper

NM_003842.5

p.P9insFs

c.26dupC

1 paper

NM_003842.5

p.A14delFs

c.40delC

1 paper

NM_003842.5

p.A14fs

c.40_41fs

1 paper

NM_003842.5

p.R15Q

c.44G>A

1 paper

NM_003842.5

p.R17G

c.49A>G

1 paper

NM_003842.5

p.P20_G21insFs

c.60_61insC

1 paper

NM_003842.5

p.P20fs

c.58_59fs

1 paper

NM_003842.5

p.E24A

c.71A>C

1 paper

NM_003842.5

p.R26P

c.77G>C