Varaico: Literature-Extracted Genetic Variants

TNFRSF11B

424 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This prot...

Pfam Domains

TNFR_c6aa 26–62UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 65–105UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 107–142UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 145–185UCSCTNFR/NGFR cysteine-rich region

Death_TNFRSF11Baa 198–269UCSCTumor Necrosis Factor Receptor Superfamily Member 11B death domain

Death_TNFRSF11Baa 273–344UCSCTumor Necrosis Factor Receptor Superfamily Member 11B death domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 11b

HGNC Previous Symbol

OPG

Papers

RefSeq ID

Protein change

DNA change

1–12 of 225 variants

82 papers

NM_002546.4

p.T55A

c.163A>G

21 papers

NM_002546.4

p.N3K

c.9C>G

15 papers

NM_002546.4

p.N3K

c.9C>A

15 papers

NM_002546.4

p.L50P

c.149T>C

8 papers

NM_002546.4

p.S322_D323Fs

c.966_969delinsCTTFs

7 papers

NM_002546.4

p.G134Splc

c.400+4C>T

7 papers

NM_002546.4

p.*402L

c.1205A>T

6 papers

NM_002546.4

p.M1R

c.2T>G

6 papers

NM_002546.4

p.Y82S

c.245A>C

6 papers

NM_002546.4

p.F117L

c.349T>C

6 papers

NM_002546.4

p.F117L

c.351C>G

6 papers

NM_002546.4

p.F117L

c.351C>A