Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

1–12 of 125 variants

4 papers

NM_014452.5

p.P202L

c.605C>T

3 papers

NM_014452.5

p.N527S

c.1580A>G

2 papers

NM_014452.5

p.S29F

c.86C>T

2 papers

NM_014452.5

p.G62S

c.184G>A

2 papers

NM_014452.5

p.P146A

c.436C>G

2 papers

NM_014452.5

p.H147R

c.440A>G

2 papers

NM_014452.5

p.F230S

c.689T>C

2 papers

NM_014452.5

p.E240*

c.718G>T

2 papers

NM_014452.5

p.A440G

c.1319C>G

2 papers

NM_014452.5

p.I618I

c.1854T>A

1 paper

NM_014452.5

p.G2A

c.5G>C

1 paper

NM_014452.5

p.T3S

c.8C>G