Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014452.5

p.V589G

c.1766T>G

Surrounding Variants

1 paper

NM_014452.5

p.R587W

c.1759C>T

1 paper

NM_014452.5

p.R613Q

c.1838G>A

1 paper

NM_014452.5

p.E617G

c.1850A>G

2 papers

NM_014452.5

p.I618I

c.1854T>A

1 paper

NM_014452.5

p.D626delFs

c.1876_1877delTC

1 paper

NM_014452.5

p.R627Q

c.1880G>A

1 paper

NM_014452.5

p.D653delFs

c.1957_1958delTC

1 paper

NM_014452.5

p.G574S

c.1720G>A

1 paper

NM_014452.5

p.C560R

c.1678T>C

1 paper

NM_014452.5

p.F550L

c.1650C>G

1 paper

NM_014452.5

p.F550L

c.1650C>A

1 paper

NM_014452.5

p.F550L

c.1648T>C