Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014452.5

p.P522T

c.1564C>A

Surrounding Variants

1 paper

NM_014452.5

p.L518R

c.1553T>G

3 papers

NM_014452.5

p.N527S

c.1580A>G

1 paper

NM_014452.5

p.A528T

c.1582G>A

1 paper

NM_014452.5

p.K529E

c.1585A>G

1 paper

NM_014452.5

p.E531Q

c.1591G>C

1 paper

NM_014452.5

p.P512L

c.1535C>T

1 paper

NM_014452.5

p.E531_N532insFs

c.1593_1594insGC

1 paper

NM_014452.5

p.L509L

c.1525C>T

1 paper

NM_014452.5

p.L536Q

c.1607T>A

1 paper

NM_014452.5

p.F549S

c.1646T>C

1 paper

NM_014452.5

p.F550L

c.1648T>C

1 paper

NM_014452.5

p.F550L

c.1650C>G