Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014452.5

p.A440G

c.1319C>G

Surrounding Variants

1 paper

NM_014452.5

p.C438C

c.1314C>T

1 paper

NM_014452.5

p.S428fs

c.1282_1283fs

1 paper

NM_014452.5

p.S428delFs

c.1282delT

1 paper

NM_014452.5

p.Y452C

c.1355A>G

1 paper

NM_014452.5

p.V426L

c.1276G>T

1 paper

NM_014452.5

p.V426L

c.1276G>C

1 paper

NM_014452.5

p.D455N

c.1363G>A

1 paper

NM_014452.5

p.A424T

c.1270G>A

1 paper

NM_014452.5

p.A459V

c.1376C>T

1 paper

NM_014452.5

p.I418F

c.1252A>T

1 paper

NM_014452.5

p.R469W

c.1405C>T

1 paper

NM_014452.5

p.S474R

c.1420A>C