Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014452.5

p.F230S

c.689T>C

Surrounding Variants

1 paper

NM_014452.5

p.R232C

c.694C>T

1 paper

NM_014452.5

p.S224_P225del0

c.670_675del6

1 paper

NM_014452.5

p.S224C

c.671C>G

2 papers

NM_014452.5

p.E240*

c.718G>T

1 paper

NM_014452.5

p.E240K

c.718G>A

1 paper

NM_014452.5

p.F217V

c.649T>G

1 paper

NM_014452.5

p.S244S

c.732C>T

1 paper

NM_014452.5

p.N209N

c.627C>T

1 paper

NM_014452.5

p.D208N

c.622G>A

4 papers

NM_014452.5

p.P202L

c.605C>T

1 paper

NM_014452.5

p.V199G

c.596T>G

1 paper

NM_014452.5

p.L193_N196delFs

c.577_586del10