Varaico: Literature-Extracted Genetic Variants

TNFRSF21

113 papers

RefSeq Summary

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal ...

Pfam Domains

TNFR_c6aa 91–131UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 171–211UCSCTNFR/NGFR cysteine-rich region

Deathaa 416–498UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 21

HGNC Alias Symbols

DR6; CD358

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014452.5

p.A145A

c.435C>A

Surrounding Variants

2 papers

NM_014452.5

p.P146A

c.436C>G

1 paper

NM_014452.5

p.H147N

c.439C>A

2 papers

NM_014452.5

p.H147R

c.440A>G

1 paper

NM_014452.5

p.T148M

c.443C>T

1 paper

NM_014452.5

p.A142T

c.424G>A

1 paper

NM_014452.5

p.V156M

c.466G>A

1 paper

NM_014452.5

p.G160R

c.478G>C

1 paper

NM_014452.5

p.G160R

c.478G>A

1 paper

NM_014452.5

p.R129*

c.385C>T

1 paper

NM_014452.5

p.S177T

c.529T>A

1 paper

NM_014452.5

p.S181P

c.541T>C

1 paper

NM_014452.5

p.D108A

c.323A>C