Varaico: Literature-Extracted Genetic Variants

Gene:TNFRSF4
Variant:p.R58C

TNFRSF4

111 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout...

Pfam Domains

TNFR_c6aa 67–107UCSCTNFR/NGFR cysteine-rich region
TNFR_c6aa 128–166UCSCTNFR/NGFR cysteine-rich region

Gene Aliases

HGNC Name

TNF receptor superfamily member 4

HGNC Previous Symbol

TXGP1L

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003327.4
p.R58C
c.172C>T
Surrounding Variants
1 paper
NM_003327.4
p.S59S
c.177C>T
1 paper
NM_003327.4
p.T62A
c.184A>G
1 paper
NM_003327.4
p.T62M
c.185C>T
1 paper
NM_003327.4
p.C64F
c.191G>T
5 papers
NM_003327.4
p.R65C
c.193C>T
1 paper
NM_003327.4
p.N50K
c.150C>G
1 paper
NM_003327.4
p.P69L
c.206C>T
1 paper
NM_003327.4
p.N73D
c.217A>G
1 paper
NM_003327.4
p.S78C
c.233C>G
1 paper
NM_003327.4
p.P80fs
c.238_239fs
1 paper
NM_003327.4
p.C81F
c.242G>T
1 paper
NM_003327.4
p.T85M
c.254C>T
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