Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 110 variants

3 papers

NM_170754.4

p.S1128G

c.3382A>G

2 papers

NM_170754.4

p.C231S

c.691T>A

2 papers

NM_170754.4

p.C231S

c.692G>C

2 papers

NM_170754.4

p.V580L

c.1738G>C

2 papers

NM_170754.4

p.V580L

c.1738G>T

2 papers

NM_170754.4

p.L1243delFs

c.3727delC

1 paper

NM_170754.4

p.S3S

c.9C>A

1 paper

NM_170754.4

p.R9S

c.27G>C

1 paper

NM_170754.4

p.L10insFs

c.28_29insC

1 paper

NM_170754.4

p.R9S

c.27G>T

1 paper

NM_170754.4

p.K28_A29insC

c.82_86ins3

1 paper

NM_170754.4

p.R40Q

c.119G>A