Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_170754.4

p.C231S

c.692G>C

Surrounding Variants

2 papers

NM_170754.4

p.C231S

c.691T>A

1 paper

NM_170754.4

p.Y230N

c.688T>A

1 paper

NM_170754.4

p.W197*

c.590G>A

1 paper

NM_170754.4

p.K237E

c.709A>G

1 paper

NM_170754.4

p.P190fs

c.568_569fs

1 paper

NM_170754.4

p.E180V

c.539A>T

1 paper

NM_170754.4

p.G156D

c.467G>A

1 paper

NM_170754.4

p.R155W

c.463C>T

1 paper

NM_170754.4

p.P149L

c.446C>T

1 paper

NM_170754.4

p.A255V

c.764C>T

1 paper

NM_170754.4

p.I140delFs

c.420delC

1 paper

NM_170754.4

p.R265W

c.793C>T