Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_170754.4

p.V381A

c.1142T>C

Surrounding Variants

1 paper

NM_170754.4

p.R374Q

c.1121G>A

1 paper

NM_170754.4

p.G393R

c.1177G>A

1 paper

NM_170754.4

p.G393R

c.1177G>C

1 paper

NM_170754.4

p.F420del1

c.1258_1259delTTT

1 paper

NM_170754.4

p.R435Q

c.1304G>A

1 paper

NM_170754.4

p.V334A

c.1001T>C

1 paper

NM_170754.4

p.L325F

c.973C>T

1 paper

NM_170754.4

p.L312V

c.934C>G

1 paper

NM_170754.4

p.Y483F

c.1448A>T

1 paper

NM_170754.4

p.Y483Y

c.1449T>C

1 paper

NM_170754.4

p.P503Fs

c.1507delinsACFs

1 paper

NM_170754.4

p.P505fs

c.1513_1514fs