Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_170754.4

p.G603E

c.1808G>A

Surrounding Variants

1 paper

NM_170754.4

p.R620*

c.1858C>T

1 paper

NM_170754.4

p.G624R

c.1870G>A

1 paper

NM_170754.4

p.G624R

c.1870G>C

2 papers

NM_170754.4

p.V580L

c.1738G>C

2 papers

NM_170754.4

p.V580L

c.1738G>T

1 paper

NM_170754.4

p.P576P

c.1728C>T

1 paper

NM_170754.4

p.G574E

c.1721G>A

1 paper

NM_170754.4

p.T571I

c.1712C>T

1 paper

NM_198316.2

p.R521L

c.1562G>T

NM_170754.4

p.R645L

c.1934G>T

1 paper

NM_170754.4

p.R555W

c.1663C>T

1 paper

NM_170754.4

p.P656L

c.1967C>T

1 paper

NM_170754.4

p.G549R

c.1645G>A