Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_170754.4

p.T924A

c.2770A>G

Surrounding Variants

1 paper

NM_170754.4

p.Q938K

c.2812C>A

1 paper

NM_170754.4

p.P877L

c.2630C>T

1 paper

NM_170754.4

p.R1013C

c.3037C>T

1 paper

NM_170754.4

p.P1024insFs

c.3072dupC

1 paper

NM_170754.4

p.P1023S

c.3067C>T

1 paper

NM_170754.4

p.P1024fs

c.3070_3071fs

1 paper

NM_170754.4

p.D1025N

c.3073G>A

1 paper

NM_170754.4

p.P1034fs

c.3100_3101fs

1 paper

NM_170754.4

p.H862Y

c.2584C>T

1 paper

NM_170754.4

p.R1077H

c.3230G>A

1 paper

NM_170754.4

p.G1081G

c.3243G>A

1 paper

NM_170754.4

p.E852K

c.2554G>A