Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_170754.4

p.S1128G

c.3382A>G

Surrounding Variants

1 paper

NM_170754.4

p.K1142Q

c.3424A>C

1 paper

NM_170754.4

p.S1146delFs

c.3436delT

1 paper

NM_170754.4

p.R1147H

c.3440G>A

1 paper

NM_170754.4

p.P1119delFs

c.3355delC

1 paper

NM_170754.4

p.G1081G

c.3243G>A

1 paper

NM_170754.4

p.R1077H

c.3230G>A

1 paper

NM_170754.4

p.P1034fs

c.3100_3101fs

1 paper

NM_170754.4

p.D1025N

c.3073G>A

1 paper

NM_170754.4

p.K1155Q

c.3463A>C

1 paper

NM_170754.4

p.P1024fs

c.3070_3071fs

1 paper

NM_170754.4

p.P1023S

c.3067C>T

1 paper

NM_170754.4

p.K1157Q

c.3469A>C