Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_170754.4

p.K1157Q

c.3469A>C

Surrounding Variants

1 paper

NM_170754.4

p.K1155Q

c.3463A>C

1 paper

NM_170754.4

p.L1163L

c.3489G>A

1 paper

NM_170754.4

p.L1178delFs

c.3532delC

1 paper

NM_170754.4

p.L1178fs

c.3532_3533fs

1 paper

NM_170754.4

p.G1192A

c.3575G>C

1 paper

NM_170754.4

p.G1192A

c.3575G>C

1 paper

NM_170754.4

p.V1195M

c.3583G>A

1 paper

NM_170754.4

p.E1205K

c.3613G>A

1 paper

NM_170754.4

p.R1147H

c.3440G>A

1 paper

NM_170754.4

p.K1212Q

c.3634A>C

1 paper

NM_170754.4

p.S1146delFs

c.3436delT

1 paper

NM_170754.4

p.K1214delFs

c.3640_3641delAA