Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_170754.4

p.L1243delFs

c.3727delC

Surrounding Variants

1 paper

NM_170754.4

p.C1242fs

c.3724_3725fs

1 paper

NM_170754.4

p.L1243fs

c.3727_3728fs

1 paper

NM_170754.4

p.P1236L

c.3707C>T

1 paper

NM_170754.4

p.I1234M

c.3702C>G

1 paper

NM_170754.4

p.S1233delFs

c.3697delT

1 paper

NM_170754.4

p.S1226F

c.3677C>T

1 paper

NM_170754.4

p.E1252K

c.3754G>A

1 paper

NM_170754.4

p.E1253delFs

c.3757delG

1 paper

NM_170754.4

p.G1215S

c.3643G>A

1 paper

NM_170754.4

p.K1214delFs

c.3640_3641delAA

1 paper

NM_170754.4

p.K1212Q

c.3634A>C

1 paper

NM_170754.4

p.M1263L

c.3787A>C