Varaico: Literature-Extracted Genetic Variants

TNS2

60 papers

RefSeq Summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in re...

Pfam Domains

C1_1aa 32–82UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

PTEN_C2aa 297–424UCSCC2 domain of PTEN tumour-suppressor protein

SH2aa 1140–1232UCSCSH2 domain

PTBaa 1275–1409UCSCPhosphotyrosine-binding domain

Gene Aliases

HGNC Name

tensin 2

HGNC Previous Symbol

TENC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_170754.4

p.V1278M

c.3832G>A

Surrounding Variants

1 paper

NM_170754.4

p.R1271H

c.3812G>A

1 paper

NM_170754.4

p.M1263L

c.3787A>C

1 paper

NM_170754.4

p.M1263L

c.3787A>T

1 paper

NM_170754.4

p.E1253delFs

c.3757delG

1 paper

NM_170754.4

p.E1252K

c.3754G>A

1 paper

NM_170754.4

p.G1360R

c.4078G>A

1 paper

NM_170754.4

p.G1360R

c.4078G>C

1 paper

NM_170754.4

p.L1243fs

c.3727_3728fs

2 papers

NM_170754.4

p.L1243delFs

c.3727delC

1 paper

NM_170754.4

p.C1242fs

c.3724_3725fs

1 paper

NM_170754.4

p.P1236L

c.3707C>T

1 paper

NM_170754.4

p.I1234M

c.3702C>G