Varaico: Literature-Extracted Genetic Variants

TP53

19,071 papers

RefSeq Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expr...

Pfam Domains

P53_TADaa 6–30UCSCP53 transactivation motif

TAD2aa 35–59UCSCTransactivation domain 2

P53aa 99–289UCSCP53 DNA-binding domain

P53_tetrameraa 319–358UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p53

HGNC Alias Symbols

p53; LFS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000546.6

p.Q331_I332Splc

c.993+7A>G

Surrounding Variants

1 paper

NM_000546.6

p.Q331_I332Splc

c.993+8G>A

1 paper

NM_000546.6

p.Q331_I332Splc

c.993+5T>C

1 paper

NM_000546.6

p.Q331_I332Splc

c.993+4C>T

2 papers

NM_000546.6

p.Q331_I332Splc

c.993+3A>T

22 papers

NM_000546.6

p.Q331_I332Splc

c.993+2T>G

20 papers

NM_000546.6

p.Q331_I332Splc

c.993+2T>C

19 papers

NM_000546.6

p.Q331_I332Splc

c.993+12T>C

13 papers

NM_000546.6

p.Q331_I332Splc

c.993+2T>A

49 papers

NM_000546.6

p.Q331_I332Splc

c.993+1G>T

15 papers

NM_000546.6

p.Q331_I332Splc

c.993+1G>C

1 paper

NM_000546.6

p.Q331_I332Splc

c.993+13G>C

84 papers

NM_000546.6

p.Q331_I332Splc

c.993+1G>A