Varaico: Literature-Extracted Genetic Variants

TP53

19,071 papers

RefSeq Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expr...

Pfam Domains

P53_TADaa 6–30UCSCP53 transactivation motif

TAD2aa 35–59UCSCTransactivation domain 2

P53aa 99–289UCSCP53 DNA-binding domain

P53_tetrameraa 319–358UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p53

HGNC Alias Symbols

p53; LFS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000546.6

p.V147delins

c.439_440delinsCC

Surrounding Variants

2 papers

NM_000546.6

p.V147insFs

c.439_440insG

1 paper

NM_000546.6

p.V147insFs

c.440_441insC

1 paper

NM_000546.6

p.V147insFs

c.440_441insA

37 papers

NM_000546.6

p.V147G

c.440T>G

13 papers

NM_000546.6

p.V147A

c.440T>C

32 papers

NM_000546.6

p.V147D

c.440T>A

24 papers

NM_000546.6

p.V147delFs

c.439delC

1 paper

NM_000546.6

p.V147delins

c.439_440delinsTG

1 paper

NM_000546.6

p.V147delins

c.439_440delinsCG

1 paper

NM_000546.6

p.V147delins

c.439_440delinsAG

1 paper

NM_000546.6

p.V147delins

c.439_440delinsTA

1 paper

NM_000546.6

p.V147delins

c.439_440delinsCA