Varaico: Literature-Extracted Genetic Variants

TP53

19,071 papers

RefSeq Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expr...

Pfam Domains

P53_TADaa 6–30UCSCP53 transactivation motif

TAD2aa 35–59UCSCTransactivation domain 2

P53aa 99–289UCSCP53 DNA-binding domain

P53_tetrameraa 319–358UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p53

HGNC Alias Symbols

p53; LFS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000546.6

p.P71_P72insFs

c.213_214ins5

Surrounding Variants

1 paper

NM_000546.6

p.P71P

c.213C>T

1 paper

NM_000546.6

p.P71P

c.213C>G

1 paper

NM_000546.6

p.P71_P72insFs

c.213_214insT

1 paper

NM_000546.6

p.P71_P72insFs

c.213_214insGG

4 papers

NM_000546.6

p.P71fs

c.211_212fs

1 paper

NM_000546.6

p.P71P

c.213C>A

2 papers

NM_000546.6

p.E68_P71del0

c.204_212del9

1 paper

NM_000546.6

p.P58_A70del13

c.172_209del39

20 papers

NM_000546.6

p.P72S

c.214C>T

9 papers

NM_000546.6

p.P71L

c.212C>T

NM_001126118.2

p.P32L

c.95C>T

51 papers

NM_000546.6

p.P72A

c.214C>G

9 papers

NM_000546.6

p.P71R

c.212C>G