Varaico: Literature-Extracted Genetic Variants

TP53

19,071 papers

RefSeq Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expr...

Pfam Domains

P53_TADaa 6–30UCSCP53 transactivation motif

TAD2aa 35–59UCSCTransactivation domain 2

P53aa 99–289UCSCP53 DNA-binding domain

P53_tetrameraa 319–358UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p53

HGNC Alias Symbols

p53; LFS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000546.6

p.L32_S33Splc

c.97-5T>C

Surrounding Variants

9 papers

NM_000546.6

p.L32_S33Splc

c.97-6C>T

1 paper

NM_000546.6

p.L32_S33Splc

c.97-4A>T

2 papers

NM_000546.6

p.L32_S33Splc

c.97-4A>G

2 papers

NM_000546.6

p.L32_S33Splc

c.97-3C>T

17 papers

NM_000546.6

p.L32_S33Splc

c.97-2A>T

1 paper

NM_000546.6

p.L32_S33Splc

c.97-8A>T

18 papers

NM_000546.6

p.L32_S33Splc

c.97-2A>G

9 papers

NM_000546.6

p.L32_S33Splc

c.97-2A>C

1 paper

NM_000546.6

p.L32_S33Splc

c.97-8A>C

14 papers

NM_000546.6

p.L32_S33Splc

c.97-1G>T

18 papers

NM_000546.6

p.L32_S33Splc

c.97-1G>C

33 papers

NM_000546.6

p.L32_S33Splc

c.97-1G>A