Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1122 variants

32 papers

NM_003722.5

p.R243W

c.727C>T

24 papers

NM_003722.5

p.P396P

c.1188A>C

21 papers

NM_003722.5

p.R319H

c.956G>A

20 papers

NM_003722.5

p.R243Q

c.728G>A

16 papers

NM_003722.5

p.R343W

c.1027C>T

16 papers

NM_003722.5

p.R343Q

c.1028G>A

15 papers

NM_003722.5

p.R266Q

c.797G>A

15 papers

NM_003722.5

p.R319C

c.955C>T

14 papers

NM_003722.5

p.C308S

c.922T>A

14 papers

NM_003722.5

p.C308S

c.923G>C

14 papers

NM_003722.5

p.R318H

c.953G>A

13 papers

NM_003722.5

p.R337Q

c.1010G>A