Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.Q110Q

c.330G>A

Surrounding Variants

1 paper

NM_003722.5

p.Q110H

c.330G>T

2 papers

NM_001114980.2

p.Q16*

c.46C>T

NM_003722.5

p.Q110*

c.328C>T

1 paper

NM_003722.5

p.T112A

c.334A>G

1 paper

NM_003722.5

p.P109S

c.325C>T

1 paper

NM_003722.5

p.N113H

c.337A>C

1 paper

NM_003722.5

p.N113K

c.339C>A

1 paper

NM_003722.5

p.L114P

c.341T>C

5 papers

NM_003722.5

p.G115W

c.343G>T

1 paper

NM_003722.5

p.G115G

c.345G>A

1 paper

NM_003722.5

p.N118T

c.353A>C

1 paper

NM_003722.5

p.N118I

c.353A>T

1 paper

NM_003722.5

p.S119G

c.355A>G