Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.M120K

c.359T>A

Surrounding Variants

1 paper

NM_003722.5

p.M120L

c.358A>C

1 paper

NM_003722.5

p.M120delFs

c.359delT

3 papers

NM_003722.5

p.M120I

c.360G>A

1 paper

NM_003722.5

p.D121G

c.362A>G

1 paper

NM_003722.5

p.S119G

c.355A>G

1 paper

NM_003722.5

p.N118T

c.353A>C

1 paper

NM_003722.5

p.N118I

c.353A>T

1 paper

NM_003722.5

p.Q123E

c.367C>G

2 papers

NM_003722.5

p.Q123insFs

c.368_369insC

1 paper

NM_003722.5

p.I124V

c.370A>G

1 paper

NM_003722.5

p.I124I

c.372T>A

1 paper

NM_003722.5

p.G115G

c.345G>A