Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.T131S

c.391A>T

Surrounding Variants

1 paper

NM_003722.5

p.T131S

c.392C>G

2 papers

NM_003722.5

p.S130F

c.389C>T

1 paper

NM_003722.5

p.S132N

c.395G>A

2 papers

NM_003722.5

p.S129S

c.387G>C

2 papers

NM_003722.5

p.S129W

c.386C>G

2 papers

NM_003722.5

p.S129L

c.386C>T

1 paper

NM_003722.5

p.P133S

c.397C>T

1 paper

NM_003722.5

p.S129P

c.385T>C

2 papers

NM_003722.5

p.S129A

c.385T>G

1 paper

NM_003722.5

p.P133L

c.398C>T

2 papers

NM_003722.5

p.S128F

c.383C>T

1 paper

NM_003722.5

p.S128T

c.382T>A