Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.S153N

c.458G>A

Surrounding Variants

1 paper

NM_003722.5

p.S153_L159insFs

c.459_477dup19

1 paper

NM_003722.5

p.S153I

c.458G>T

1 paper

NM_003722.5

p.S153G

c.457A>G

1 paper

NM_003722.5

p.P152R

c.455C>G

1 paper

NM_003722.5

p.P152L

c.455C>T

1 paper

NM_003722.5

p.S154F

c.461C>T

1 paper

NM_003722.5

p.P152T

c.454C>A

1 paper

NM_003722.5

p.P152A

c.454C>G

1 paper

NM_003722.5

p.P152S

c.454C>T

1 paper

NM_003722.5

p.T155insFs

c.464dupC

1 paper

NM_003722.5

p.T155P

c.463A>C

1 paper

NM_003722.5

p.T155A

c.463A>G