Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003722.5

p.A164T

c.490G>A

Surrounding Variants

1 paper

NM_003722.5

p.A164S

c.490G>T

1 paper

NM_003722.5

p.S162L

c.485C>T

1 paper

NM_003722.5

p.P166S

c.496C>T

1 paper

NM_001114980.2

p.S68delFs

c.203delC

5 papers

NM_003722.5

p.P166L

c.497C>T

1 paper

NM_003722.5

p.P161S

c.481C>T

1 paper

NM_003722.5

p.S167P

c.499T>C

1 paper

NM_003722.5

p.S167F

c.500C>T

1 paper

NM_003722.5

p.L159insFs

c.477dupC

1 paper

NM_003722.5

p.T169I

c.506C>T

1 paper

NM_003722.5

p.D170N

c.508G>A

1 paper

NM_003722.5

p.D170Y

c.508G>T