Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.H175_S176ins15

c.523_527ins45

Surrounding Variants

1 paper

NM_003722.5

p.H175fs

c.523_524fs

1 paper

NM_003722.5

p.H175L

c.524A>T

1 paper

NM_003722.5

p.H175_S176delFs

c.525_526delCA

1 paper

NM_003722.5

p.P174L

c.521C>T

1 paper

NM_003722.5

p.P174_H175insT

c.520_524ins3

1 paper

NM_003722.5

p.P174S

c.520C>T

7 papers

NM_003722.5

p.G173D

c.518G>A

1 paper

NM_003722.5

p.G173A

c.518G>C

6 papers

NM_003722.5

p.G173V

c.518G>T

1 paper

NM_003722.5

p.S176R

c.528T>A

1 paper

NM_003722.5

p.P172Q

c.515C>A

1 paper

NM_003722.5

p.P172L

c.515C>T