Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003722.5

p.S180ins1

c.539_540insTTC

Surrounding Variants

4 papers

NM_003722.5

p.S180T

c.538T>A

2 papers

NM_003722.5

p.S180F

c.539C>T

2 papers

NM_003722.5

p.V179M

c.535G>A

1 paper

NM_003722.5

p.V179L

c.535G>C

1 paper

NM_003722.5

p.V179L

c.535G>T

1 paper

NM_003722.5

p.F181L

c.541T>C

1 paper

NM_003722.5

p.D178Y

c.532G>T

1 paper

NM_003722.5

p.F177F

c.531C>T

1 paper

NM_003722.5

p.S176R

c.528T>A

1 paper

NM_003722.5

p.Q183R

c.548A>G

1 paper

NM_003722.5

p.H175L

c.524A>T

1 paper

NM_003722.5

p.H175_S176ins15

c.523_527ins45