Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.K188N

c.564G>C

Surrounding Variants

1 paper

NM_003722.5

p.K188N

c.564G>T

1 paper

NM_003722.5

p.K188T

c.563A>C

1 paper

NM_003722.5

p.K188R

c.563A>G

1 paper

NM_003722.5

p.K188M

c.563A>T

1 paper

NM_003722.5

p.K188E

c.562A>G

3 papers

NM_003722.5

p.S189L

c.566C>T

2 papers

NM_003722.5

p.A190_W192delFs

c.569_576del8

1 paper

NM_003722.5

p.A187A

c.561C>A

4 papers

NM_003722.5

p.A187A

c.561C>G

1 paper

NM_003722.5

p.A187V

c.560C>T

1 paper

NM_003722.5

p.A190T

c.568G>A

1 paper

NM_003722.5

p.A190P

c.568G>C