Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_003722.5

p.K233E

c.697A>G

Surrounding Variants

4 papers

NM_003722.5

p.K232E

c.694A>G

6 papers

NM_003722.5

p.Y231C

c.692A>G

2 papers

NM_003722.5

p.Y231D

c.691T>G

1 paper

NM_003722.5

p.V230_A234delins

c.690_702delinsCACCTGAACCCCC

1 paper

NM_003722.5

p.V230V

c.690C>T

1 paper

NM_003722.5

p.Y231_K232del2

c.691_695del6

1 paper

NM_003722.5

p.H236R

c.707A>G

1 paper

NM_003722.5

p.V237F

c.709G>T

1 paper

NM_003722.5

p.V237D

c.710T>A

1 paper

NM_003722.5

p.M228V

c.682A>G

1 paper

NM_003722.5

p.T238M

c.713C>T

3 papers

NM_003722.5

p.A227T

c.679G>A