Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.E255D

c.765G>C

Surrounding Variants

1 paper

NM_003722.5

p.G256E

c.767G>A

1 paper

NM_003722.5

p.E255*

c.763G>T

1 paper

NM_003722.5

p.N254K

c.762C>A

1 paper

NM_003722.5

p.N254K

c.762C>G

1 paper

NM_003722.5

p.N254N

c.762C>T

1 paper

NM_003722.5

p.F253L

c.759C>A

1 paper

NM_003722.5

p.G256Splc

c.766+5G>A

1 paper

NM_003722.5

p.F253L

c.757T>C

1 paper

NM_003722.5

p.E252D

c.756A>C

1 paper

NM_003722.5

p.E252D

c.756A>T

1 paper

NM_003722.5

p.R251fs

c.751_752fs

1 paper

NM_003722.5

p.S250N

c.749G>A