Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.Q257*

c.769C>T

Surrounding Variants

1 paper

NM_003722.5

p.Q257E

c.769C>G

1 paper

NM_003722.5

p.G256E

c.767G>A

1 paper

NM_003722.5

p.Q257Q

c.771G>A

1 paper

NM_003722.5

p.G256Splc

c.767-1G>A

1 paper

NM_003722.5

p.A259V

c.776C>T

1 paper

NM_003722.5

p.P260L

c.779C>T

2 papers

NM_003722.5

p.P261A

c.781C>G

1 paper

NM_003722.5

p.L264V

c.790T>G

2 papers

NM_003722.5

p.L264S

c.791T>C

1 paper

NM_003722.5

p.L264L

c.792G>A

1 paper

NM_003722.5

p.L264F

c.792G>C

1 paper

NM_003722.5

p.L264F

c.792G>T