Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.G269V

c.806G>T

Surrounding Variants

2 papers

NM_003722.5

p.G269E

c.806G>A

1 paper

NM_003722.5

p.E268D

c.804G>T

1 paper

NM_003722.5

p.E268G

c.803A>G

2 papers

NM_003722.5

p.E268K

c.802G>A

1 paper

NM_003722.5

p.E268_H272del0

c.802_816del15

1 paper

NM_003722.5

p.S271N

c.812G>A

5 papers

NM_003722.5

p.S271T

c.812G>C

3 papers

NM_003722.5

p.V267I

c.799G>A

15 papers

NM_003722.5

p.R266Q

c.797G>A

1 paper

NM_003722.5

p.R266P

c.797G>C

1 paper

NM_003722.5

p.R266G

c.796C>G

2 papers

NM_003722.5

p.R266*

c.796C>T