Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.I280delFs

c.838delA

Surrounding Variants

1 paper

NM_003722.5

p.P279T

c.835C>A

1 paper

NM_003722.5

p.P279A

c.835C>G

1 paper

NM_003722.5

p.T281A

c.841A>G

1 paper

NM_003722.5

p.T281R

c.842C>G

1 paper

NM_003722.5

p.G282E

c.845G>A

2 papers

NM_003722.5

p.E277delFs

c.829delG

1 paper

NM_003722.5

p.V276A

c.827T>C

1 paper

NM_003722.5

p.V276L

c.826G>T

1 paper

NM_003722.5

p.Q284delFs

c.850_851delCA

1 paper

NM_003722.5

p.Q284insFs

c.850_851ins4

1 paper

NM_003722.5

p.Q284fs

c.850_851fs

1 paper

NM_003722.5

p.S285delFs

c.853_854delAG