Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003722.5

p.M307L

c.919A>C

Surrounding Variants

1 paper

NM_003722.5

p.M307L

c.919A>T

2 papers

NM_003722.5

p.M307I

c.921G>A

2 papers

NM_003722.5

p.M307I

c.921G>C

2 papers

NM_003722.5

p.M307I

c.921G>T

14 papers

NM_003722.5

p.C308S

c.922T>A

8 papers

NM_003722.5

p.C308Y

c.923G>A

14 papers

NM_003722.5

p.C308S

c.923G>C

1 paper

NM_003722.5

p.C308F

c.923G>T

1 paper

NM_003722.5

p.N309D

c.925A>G

1 paper

NM_003722.5

p.N309K

c.927C>A

1 paper

NM_003722.5

p.N309K

c.927C>G

1 paper

NM_003722.5

p.S310N

c.929G>A