Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.S311delFs

c.933delT

Surrounding Variants

6 papers

NM_003722.5

p.S311N

c.932G>A

1 paper

NM_003722.5

p.S311T

c.932G>C

3 papers

NM_003722.5

p.S311G

c.931A>G

3 papers

NM_003722.5

p.C312Y

c.935G>A

1 paper

NM_003722.5

p.S310N

c.929G>A

2 papers

NM_003722.5

p.S310T

c.929G>C

1 paper

NM_003722.5

p.C312F

c.935G>T

1 paper

NM_003722.5

p.N309K

c.927C>A

1 paper

NM_003722.5

p.N309K

c.927C>G

1 paper

NM_003722.5

p.N309D

c.925A>G

1 paper

NM_003722.5

p.G314*

c.940G>T

8 papers

NM_003722.5

p.C308Y

c.923G>A