Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.M316L

c.946A>C

Surrounding Variants

1 paper

NM_003722.5

p.M316V

c.946A>G

1 paper

NM_003722.5

p.M316L

c.946A>T

2 papers

NM_003722.5

p.M316I

c.948G>A

1 paper

NM_003722.5

p.G315E

c.944G>A

2 papers

NM_003722.5

p.M316I

c.948G>C

2 papers

NM_003722.5

p.M316I

c.948G>T

1 paper

NM_003722.5

p.G315_M316insA

c.943_947ins3

3 papers

NM_003722.5

p.G315W

c.943G>T

1 paper

NM_003722.5

p.N317S

c.950A>G

1 paper

NM_003722.5

p.G315_R318del4

c.943_953del12

2 papers

NM_003722.5

p.G314E

c.941G>A

2 papers

NM_003722.5

p.R318S

c.952C>A