Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_003722.5

p.R318C

c.952C>T

Surrounding Variants

2 papers

NM_003722.5

p.R318S

c.952C>A

14 papers

NM_003722.5

p.R318H

c.953G>A

1 paper

NM_003722.5

p.N317S

c.950A>G

3 papers

NM_003722.5

p.R319S

c.955C>A

15 papers

NM_003722.5

p.R319C

c.955C>T

22 papers

NM_003722.5

p.R319H

c.956G>A

NM_001114980.2

p.R225H

c.674G>A

2 papers

NM_003722.5

p.M316I

c.948G>A

2 papers

NM_003722.5

p.M316I

c.948G>C

6 papers

NM_003722.5

p.R319L

c.956G>T

NM_001114980.2

p.R225L

c.674G>T

2 papers

NM_003722.5

p.M316I

c.948G>T

1 paper

NM_003722.5

p.M316L

c.946A>C

1 paper

NM_003722.5

p.M316V

c.946A>G