Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.R338G

c.1012C>G

Surrounding Variants

3 papers

NM_003722.5

p.R338C

c.1012C>T

2 papers

NM_003722.5

p.R338H

c.1013G>A

13 papers

NM_003722.5

p.R337Q

c.1010G>A

NM_001114980.2

p.R243Q

c.728G>A

1 paper

NM_003722.5

p.R337P

c.1010G>C

6 papers

NM_003722.5

p.R337L

c.1010G>T

6 papers

NM_003722.5

p.R337G

c.1009C>G

1 paper

NM_003722.5

p.F340L

c.1018T>C

1 paper

NM_003722.5

p.L335L

c.1005G>A

1 paper

NM_003722.5

p.F340L

c.1020T>A

1 paper

NM_003722.5

p.L335P

c.1004T>C

1 paper

NM_003722.5

p.F340L

c.1020T>G

1 paper

NM_003722.5

p.A342T

c.1024G>A