Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.A346S

c.1036G>T

Surrounding Variants

3 papers

NM_003722.5

p.A346D

c.1037C>A

10 papers

NM_003722.5

p.A346G

c.1037C>G

1 paper

NM_003722.5

p.C345W

c.1035T>G

6 papers

NM_003722.5

p.C347S

c.1039T>A

2 papers

NM_003722.5

p.C345R

c.1033T>C

1 paper

NM_003722.5

p.C347R

c.1039T>C

4 papers

NM_003722.5

p.C347Y

c.1040G>A

5 papers

NM_003722.5

p.C347S

c.1040G>C

8 papers

NM_003722.5

p.C347F

c.1040G>T

1 paper

NM_003722.5

p.C347W

c.1041C>G

1 paper

NM_003722.5

p.I344T

c.1031T>C

1 paper

NM_003722.5

p.I344delFs

c.1031delT