Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.G349delins

c.1045_1046delinsTT

Surrounding Variants

1 paper

NM_003722.5

p.G349R

c.1045G>A

7 papers

NM_003722.5

p.G349E

c.1046G>A

1 paper

NM_003722.5

p.G349del1

c.1045_1046delGGA

1 paper

NM_003722.5

p.R350G

c.1048A>G

4 papers

NM_003722.5

p.P348S

c.1042C>T

1 paper

NM_003722.5

p.C347W

c.1041C>G

2 papers

NM_003722.5

p.R350K

c.1049G>A

1 paper

NM_003722.5

p.R350S

c.1050A>C

1 paper

NM_003722.5

p.R350S

c.1050A>T

4 papers

NM_003722.5

p.C347Y

c.1040G>A

5 papers

NM_003722.5

p.C347S

c.1040G>C

8 papers

NM_003722.5

p.C347F

c.1040G>T