Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.Q362P

c.1085A>C

Surrounding Variants

1 paper

NM_003722.5

p.V364I

c.1090G>A

1 paper

NM_003722.5

p.R360T

c.1079G>C

2 papers

NM_003722.5

p.S365L

c.1094C>T

1 paper

NM_003722.5

p.I359V

c.1075A>G

1 paper

NM_003722.5

p.S365S

c.1095G>A

1 paper

NM_003722.5

p.S365_D366insFs

c.1095_1096insC

1 paper

NM_003722.5

p.D366N

c.1096G>A

1 paper

NM_003722.5

p.D357N

c.1069G>A

1 paper

NM_003722.5

p.S367S

c.1101T>C

2 papers

NM_003722.5

p.T368_K369insC

c.1102_1106ins3

1 paper

NM_003722.5

p.T368A

c.1102A>G

1 paper

NM_003722.5

p.K369insFs

c.1106dupA