Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.K369insFs

c.1106dupA

Surrounding Variants

2 papers

NM_003722.5

p.T368_K369insC

c.1102_1106ins3

1 paper

NM_003722.5

p.T368_K369insFs

c.1104_1105insT

1 paper

NM_003722.5

p.T368A

c.1102A>G

1 paper

NM_003722.5

p.S367S

c.1101T>C

1 paper

NM_003722.5

p.N370fs

c.1108_1109fs

1 paper

NM_003722.5

p.N370Y

c.1108A>T

4 papers

NM_003722.5

p.N370S

c.1109A>G

1 paper

NM_003722.5

p.D366N

c.1096G>A

1 paper

NM_003722.5

p.S365S

c.1095G>A

1 paper

NM_003722.5

p.S365_D366insFs

c.1095_1096insC

2 papers

NM_003722.5

p.S365L

c.1094C>T

1 paper

NM_003722.5

p.G371D

c.1112G>A