Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.K391N

c.1173G>C

Surrounding Variants

1 paper

NM_003722.5

p.K391N

c.1173G>T

1 paper

NM_003722.5

p.K391T

c.1172A>C

1 paper

NM_003722.5

p.K391*

c.1171A>T

1 paper

NM_003722.5

p.I390I

c.1170C>T

4 papers

NM_003722.5

p.R393Q

c.1178G>A

1 paper

NM_003722.5

p.S389S

c.1167C>T

1 paper

NM_003722.5

p.R394K

c.1181G>A

3 papers

NM_003722.5

p.S389A

c.1165T>G

2 papers

NM_003722.5

p.T388I

c.1163C>T

1 paper

NM_003722.5

p.M387L

c.1159A>C

1 paper

NM_003722.5

p.P396_D397insFs

c.1188_1189insCC

24 papers

NM_003722.5

p.P396P

c.1188A>C