Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.E399K

c.1195G>A

Surrounding Variants

1 paper

NM_003722.5

p.E399G

c.1196A>G

1 paper

NM_003722.5

p.E399D

c.1197A>C

1 paper

NM_003722.5

p.E399D

c.1197A>T

1 paper

NM_003722.5

p.D398N

c.1192G>A

1 paper

NM_003722.5

p.D397N

c.1189G>A

1 paper

NM_003722.5

p.P396_D397insFs

c.1188_1189insCC

24 papers

NM_003722.5

p.P396P

c.1188A>C

1 paper

NM_003722.5

p.D397delFs

c.1189delG

1 paper

NM_003722.5

p.Y402H

c.1204T>C

1 paper

NM_003722.5

p.R394K

c.1181G>A

4 papers

NM_003722.5

p.R393Q

c.1178G>A

1 paper

NM_003722.5

p.K391N

c.1173G>C