Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

1–12 of 283 variants

15 papers

NM_005427.4

p.A2T

c.4G>A

12 papers

NM_005427.4

p.T5I

c.14C>T

8 papers

NM_005427.4

p.P425L

c.1274C>T

6 papers

NM_005427.4

p.P405R

c.1214C>G

4 papers

NM_005427.4

p.R362Q

c.1085G>A

3 papers

NM_005427.4

p.T7I

c.20C>T

3 papers

NM_005427.4

p.L54R

c.161T>G

3 papers

NM_005427.4

p.P124P

c.372C>T

3 papers

NM_005427.4

p.T136M

c.407C>T

3 papers

NM_005427.4

p.N220S

c.659A>G

3 papers

NM_005427.4

p.R269Q

c.806G>A

3 papers

NM_005427.4

p.R310Q

c.929G>A